Cannabinoids-Promising Antimicrobial Drugs or Intoxicants with Benefits?

Harvesting Benefits from Cannabinoids

With the ongoing liberalization of cannabis laws in many parts of the United States that are decriminalizing its recreational and/or medical use, there is much discussion about the benefits of cannabinoids and how to mitigate potential negative societal repercussions of increased access to them. At risk of being overshadowed amidst this debate is the fascinating biology coming to light about ho...

Cannabinoids: Pharmacological profile of promising molecules

Cannabinoid research has gained remarkable interest in the past ten years after the discoveries of endogenous compounds with cannabimimetic activity and identification of their molecular targets, CB1 and CB2 receptors. Subsequently, attention has focused on putative therapeutic applications of cannabinoids. The non-psychotropic cannabidiol (CBD), some analogues of natural cannabinoids and their...

Antimicrobial Peptides: Primeval Molecules or Future Drugs?

1 Graduate Program in Life Sciences, Microbiology and Immunology Program, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America, 2 Department of Microbial Pathogenesis, Dental School, University of Maryland, Baltimore, Maryland, United States of America, 3 Department of Microbiology and Immunology, School of Medicine, University of Maryland, Baltimore, Maryla...

Miscellaneous natural intoxicants

Synthetic cannabinoids as drugs of abuse.

In the last decade a number of products have appeared in various countries that contain synthetic cannabinoids. This article reviews the history of the sale of these drugs, and the evidence that they contain synthetic cannabinoids. The biochemistry of the synthetic cannabinoids identified thus far is discussed, including a discussion of chemical structures and biochemical targets. The cannabino...